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Apoptosis and Aging

me string, as it literally translates from Latin, is known as a telomere (Cech). The telomere, a short string of amino acids, contains the error correcting information required to properly duplicate DNA, however with each unzip the telomere becomes shorter, until it is gone. The absence of the telomere results damaged DNA, thus triggering apoptosis (Agin, Cech). DNA can also be damaged by exposure to forms of radiation including ultra-violet radiation from the sun. As stated any damage to the genetic material results in a triggering of apoptosis (Schneider 67). The length of the telomere string is what limits the number of times the particular cell can divide, and by passing this information on to its issue, similarly limits any descendants to similar division. This is the safety mechanism that prevents normal cells from growing out of control and becoming a malignancy. Failure of this safety mechanism is what is seen in cells of breast cancer tumors (Cech). The telomere theory is only one of many that allege controls over the apoptotic processes, but is the leading focus of research for cancer centers through out the world. Other leading theories include, hormonal control, and protein signaling devices, referred to as factors, a term often associated with compounds of either unknown origin or affect (Leeuwenburgh 2.0, Cotran 76, Cech). Some common threads do exist among apposing theorists, in particular; the very genes that may hold the keys to eternal life, are the genes that allow cancer to spread. If these genes are disabled cancer is the result. Apoptosis, as stated, is the natural regulatory mechanism by which cancerous cells would be eradicated. In order for our technology to achieve control over this phenomenon, we must first learn to control our leading killer today, cancer (Cech). After careful scrutiny of the latest research, as detailed herein, this technology is beyond our present grasp. Some day soon, we may...

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