hat you can never trust the people that you call your friends, he is saying to be careful of those who call you a friend but only think of themselves while saying it. Even after spending the majority of his life calling Lennie a friend, George still betrayed him for the chance to become who he wanted to be. The animalistic nature of people tends to come out when they have the chance to seize what they believe is rightfully ours. So don't trust everyone who can trust you because everyone has got an agenda in life that shows us where they want to be. If you stand in the way of obtaining their goal they may be likely to step over you to get to it. As George has showed us, the human trait of loyalty can become very weak if put through the test of time, so avoid trying to test it so that you may not end up as Lennie did, being treated no better than an old man's dog....
