neurons in the brain, preventing them from breaking down. This drug's response rate is also very low, though it's exact numbers are unknown. Some other cholinesterase inhibitors in testing are Physostigmine SR, ENA 713, NXX 066, and Galanthamine.Future ResearchThere are two new breakthroughs in the research of Alzheimer's that might help find a cure. The first is a vaccine that was injected into a special breed of mice. These mice were bred to have similar plaque build ups in the brain. This vaccine reduced the plaque up to 60%. The drug also stimulated the immune system to produce antibodies that get rid of the amyloid fragments that cause neurotic plaques. Along with this, amyloid protein build up still occurs, which is still puzzling researchers.The second breakthrough is a new protein that has been linked to Alzheimer's Disease. This protein, nicastrin, has always been thought to work with presenilin to form pepsids. Now it's suspected of helping with the formation of plaques. The next thing researcher's have to do is find the protein's 3D shape. This will help with the development of a drug that will bind to the nicastrin, and hopefully disrupt the formation of the plaques, preventing symptoms of Alzheimer's.If these two potential treatments are researched more, there is hope for a cure in the years to come....
