H inactivates drug•Powder mixed in prepared fruit for infants, children•Whole, not crushed or chewed (enteric coated)•Low-fat diet to decrease GI symptoms•Powder mixed with pureed fruit; take tabs with or before foodPerform/provide:•Storage in tight container at room temperatureEvaluate:•FOR ALLERGY TO PORKDIGOXINDigoxin, Lanoxicaps, LanoxinFunc. class.: Antidysrhythmic, cardiac glycosideChem. class.: Digitalis preparationAction: Inhibits the sodium-potassium ATPase, which makes more calcium available for contractile proteins, resulting in increased cardiac outputUses: CHF, atrial fibrillation, atrial flutter, atrial tachycardia, rapid digitalization in these disordersDosage and routes:•Adult: IV 0.5 mg given over *5 min, then PO 0.125-0.5 mg qd in divided doses q4-6hr as needed•Elderly: PO 0.125 mg qd maintenance•Child *2 yr: PO 0.02-0.04 mg/kg divided q8h over 24 hr; maintenance 0.006-0.012 mg/kg qd in divided doses q12hr; IV loading dose 0.015-0.035 mg/kg over *5 min•Child 1 mo-2 yr: IV 0.03-0.05 mg/kg in divided doses over *5 min q48h; change to PO as soon as possible; PO 0.035-0.060 mg/kg divided in 3 doses over 24 hr; maintenance 0.01-0.02 mg/kg in divided doses q12h•Neonates: IV loading dose 0.02-0.03 mg/kg over *5 min in divided doses q4-8h; change to PO as soon as possible; PO loading dose 0.035 mg/kg divided q8h over 24h; maintenance 0.01 mg/kg in divided doses q12hr•Premature infants: IV 0.015-0.025 mg/kg divided in 3 doses over 24 hr, given over *5 min; maintenance 0.003-0.009 mg/kg in divided doses q12hAvailable forms: Caps 50, 100, 200 mg; elix 50 mg/ml; tabs 125, 250, 500 mg; inj 100, 250 mg/mlSide effects/adverse reactions:CNS:Headache, drowsiness, apathy, confusion, disorientation, fatigue, depression, hallucinationsCV:Dysrhythmias, hypotension, bradycardia, AV blockEENT:Blurred vision, yellow-green halos, photophobia, diplopiaGI:Nausea, vomiting, a...
