dria is presentPerform/provide:•Storage in tight container at room temperatureEvaluate:•Therapeutic response: decreased fever, malaise, rash, negative C&S for infecting organismTeach patient/family:•That long-term therapy may be needed to clear infection (1 wk-6 mo depending on infection)•To avoid hazardous activities if dizziness occurs•To take 2 hr ac administration of other drugs that increase gastric pH (antacids, H2-blockers, anticholinergics)•Importance of compliance with drug regimen•To notify physician if GI symptoms, signs of liver dysfunction (fatigue, nausea, anorexia, vomiting, dark urine, pale stools)ISOSORBIDEIsmoticFunc. class.: Miscellaneous ophthalmic agentAction: Increases osmotic gradient between plasma and ocular fluids, which decreases intraocular pressureUses: Reduces intraocular pressure from glaucoma and cataract surgeryDosage and routes:•Adult: PO 1.5 g/kg, then increase to 1-3 g/kg bid-qidAvailable forms: Sol 45%Side effects/adverse reactions:CNS:Headache, light-headedness, irritability, lethargy, syncope, confusion, dizziness, vertigo, disorientationGI:Nausea, vomiting, anorexia, diarrhea, cramps, thirstINTEG:RashMETA:Hypernatremia, hyperosmolarityContraindications: Hypersensitivity, anuria, severe renal disease, pulmonary edema, hemorrhagic glaucoma, dehydrationPrecautions: Pregnancy , patients on Na-restricted dietNURSING CONSIDERATIONSAssess:•I&O; report decrease in urinary output•Electrolytes during treatmentAdminister:•After pouring over ice (oral)Evaluate:•Therapeutic response: decreased intraocular pressureLEVOTHYROXINE SODIUMFunc. class.: Thyroid hormoneChem. class.: Levoisomer of thyroxineAction: Increases metabolic rates, increases cardiac output, O2 consumption, body temperature, blood volume, growth, development at cellular levelUses: Hypothyroidism, myxedema coma, thyroid hormone replacement, cretinism, thyrotoxicosisDosage an...
