n the corpus cavernosum, in the penis. This relaxation is necessary to allow the inflow of blood, which is what causes an erection to occur. However, in a male with erectile dysfunction, phosphodiesterase type 5 is “responsible for degradation of cylic guanosine monophosphate” (FDA, par. 3). Thus, the smooth muscle is unable to relax to allow the inflow of blood. This results in the inability to gain and maintain and erection. Sildenafil works by inhibiting the phosphodiesterase type 5. As a result, there is no inhibition of the cylic guanine monophosphate. Thus the smooth muscle is able to relax and allow the inflow of blood necessary for erection (FDA, par. 4). Behavioral effectsThus by examining the mechanisms of action, the myth that Sildenafil causes sexual excitation or that the drug is an aphrodisiac, is dispelled. Rather, it is understood that the drug simply allows the natural response to sexual excitation to occur, rather than causing the excitation itself. Because of the drug’s effects, the use of the drug is associated with some behavioral changes. Those who suffer from erectile dysfunction often have anxiety and lack on confidence in regards to sexual functioning. They may in fact avoid situation in which they may feel sexually inadequate. Obviously, this can result in a less than satisfactory sex-life. Because Sildenafil is able to provide normal sexual functioning for most of those who take it, it naturally follows that users can experience a renewal in their self-confidence and a decrease of their sexual anxieties regarding problems with erection, as they are able to maintain and enjoy a normal sex-life. [Note: none of the material in the preceding paragraph was taken from another source.]Physiological Side EffectsLike most drugs, Sildenafil does have side effects, but the side effects “when they occur, are usually mild and temporary” (FDA, par. 6). One of these side effects is a temporary c...
