must be restrained it is to be limited to brief periods of around three minutes (United States Department of Agriculture 3). This is similar to the procedure followed when a doctor holds a child to administer a vaccination shot. For all surgeries and painful tests, sedatives and anesthetics must be utilized (United States Department of Agriculture 49). If the test will leave the animal permanently damaged, euthanasia must be administered before the anesthetic wears off (United States Department of Agriculture 48). For humans this topic is still being debated, but animals are put to sleep every day when an owner or veterinarian decides the quality of the animal's life will be too low for it to go on living. These few but important changes in animal research legislation have aided in improving animal welfare. PETA believes that the benefits of animal research do not outweigh the costs when alternatives are available; proponents argue that those alternatives are not effective. PETA's stance is that animal life is too valuable to risk on experimentation especially when there are alternatives, such as false human skin grown in culture, computer programs, and using human subjects. Taking a few skin cells and growing them into small squares of skin produces the false human skin. This piece of "skin" can be used to test irritation reactions to different chemicals. It is being used in the cosmetic industry, which has all but ceased animal testing. One problem with the false skin however is that it can only be exposed to water-soluble chemicals or it suffers extreme damage (D.E. 168). Furthermore, it currently contains no melanocytes, the chemicals that give skin its color, or immune cells (D.E. 168). It is not known how or if these substances effect any laboratory setting, but it is desirable for any experiment to mimic real life situations as closely as possible. Another alternative to actual animal experimentation is using computer simulations...