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Myasthenia Gravis

tory muscles, are also symptoms of MG. This disorder is also involved with vision changes, double vision, difficulty maintaining steady gaze, frequent gagging or choking, a difficulty talking or chewing, weakness or paralysis that worsens with exertion later in the day, a droopy head, along with poor posture, a difficulty climbing stairs and lifting heavy things, a need to use hands to arise from sitting position, and lastly weakness and paralysis improving with rest(Howard). CausesIs a group of diseases, affecting the neuromuscular junction. congenital myasthenia syndrome (CMS, or CMG) is a "cousin" disease that is genetic in nature, meaning the body has a flaw in the chromosomes(Addoub,1996). “MG involves fluctuating levels of weakness of commonly used muscles. Weakness occurs when the nerve impulse does not adequately reach the muscle cells; this is caused by blockage of the action of neurotransmitters (the specific chemicals that transmit signals from nerve cell to muscle cell). Acetylcholine RECEPTORS on the muscles are actually destroyed by the immune system, thus it is an immune response of the body against itself. High levels of antibodies block the action of neurotransmitters(Howard). Myasthenia gravis typically targets skeletal muscles, where the nicotinic acetylcholine receptors are located. The muscles innervated by the cranial nerves are often the first and worst affected(Adduob,1996)Even though this is considered an autoimmune disorder such as this form of Myasthenia Gravis the actual cause of these autoimmune disorders is unknown. “In some cases, it may be associated with tumors of the thymus (a tissue of the immune system). It also may be associated with hyperthyroidism/thyrotoxicosis, rheumatoid arthritis, Lupus (systemic lupus erythematosus), and other immune system disorders. In many cases, no other disorder is identified”(Howard). TreatmentNo cure for myasthenia gravis has been found. Therefore, ...

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