ent of patients with tuberculosis in the Moabit Hospital located in Berlin. Paul Ehrlich married a nineteen-year-old Hedwig Pinkus in 1883. Almost a year later Ehrlich made titular professor at Berlin. In 1887, he became a teacher at the University of Berlin but because of anti-Semitic feelings, he was not paid. Ehrlich contracted tuberculosis because of his laboratory work. He and his wife went to Egypt so he could recover and they returned three years later in 1890. With the discovery of Koch's new tuberculin treatment Ehrlich never had a recurrence. In the same year, Robert Koch appointed Ehrlich as one of his assistants at the Institute for Infectious Diseases. Here, Ehrlich begins the immunological studies that make him famous.Ehrlich first developed the side-chain theory in which he demonstrated how one of the two different chemical groups in the toxin molecule aligns the toxin molecule to the side-chains or receptors, which exposing the cell to damage. In 1907, he synthesized several hundred derivative compounds from atoxyl. Ehrlich's work was dedicated mainly to the study of chemotherapy. He wanted to find chemical substances that have special affinities for pathogenic organisms so he could cure diseases. When the cause of syphilis was discovered, Ehrlich decided to look for a drug that would be effective against the cause. On April 1910, he announced the invention of number 606(Salvarsan), which was proved to efficient against syphilis. With more investigation, it was found out that the 914th arsenical substance, although less effective, was more practical. In 1914, his health declined and after a small stroke, he entered a sanatorium for treatment. On August 20, 1915 in Homburg, Germany Paul Ehrlich died from another stroke.During Paul Ehrlich's lifetime, he was awarded many honors. He was a mem...
