lincomycin, polymyxin B, promethazine, tetracycline, Vit B with CLab test interferences:False positive: Urine glucose, urine protein, Coombs’ testNURSING CONSIDERATIONSAssess:•I&O ratio; report hematuria, oliguria, since penicillin in high doses is nephrotoxic•Any patient with compromised renal system, since drug is excreted slowly in poor renal system function; toxicity may occur rapidly•Liver studies: AST, ALT•Blood studies: WBC, RBC, H&H, bleeding time•Renal studies: urinalysis, protein, blood•C&S before drug therapy; drug may be taken as soon as culture is taken•Bowel pattern before and during treatment•Skin eruptions after administration of penicillin to 1 wk after discontinuing drug•Respiratory status: rate, character, wheezing, tightness in chest•Allergies before initiation of treatment, reaction of each medication; highlight allergies on chart, KardexAdminister:•IV after diluting 1 g or less/5 ml or more sterile H2O or 0.9% NaCl; shake; give dose over 3-5 min; may further dilute to 50-100 ml with D5W, 0.9% NS, and give over hr; discontinue primary IV•Drug after C&S has been completedPerform/provide:•Adrenalin, suction, tracheostomy set, endotracheal intubation equipment on unit•Adequate intake of fluids (2 L) during diarrhea episodes•Scratch test to assess allergy after securing order from physician; usually done when penicillin is only drug of choice•Storage at room temperature, reconstituted solution for 24 hr or 7 days refrigeratedEvaluate:•Therapeutic response: absence of fever, purulent drainage, redness, inflammationTeach patient/family:•That culture may be taken after completed course of medication•To report sore throat, fever, fatigue; (may indicate superimposed infection)•To wear or carry Medic Alert ID if allergic to penicillins•To notify nurse of diarrheaTreatment of overdose: Withdraw ...
